Genomodifikatsvats aytsere karox en qaxtskexe buzhox dexamijotsov kat tal
Aytseri ognutyamb tsetuksimab dexamijotsi zangvatsayin artadrutyan shnorhiv gitnakannere huys unen buzhel kolorektalayin qaxtskexe, toqeri qaxtskexe ev ayl hivandutyunner՝ aveli matcheli gnerov:
Verjin tasnamyaknerum hetazotoxnere qaxtskexi dem payqari hamar bazmitss en dimel hakamarminnerin՝ mardu imunayin hamakargi himnakan zenqin: Ayn depqum, erb imunayin hamakarge sovorabar hakamarminneri mets xumb e ogtagortsum patogeni tarber maseri vra azdelu hamar, orosh hakamarminner unak en tshanachelu miak arandznahatuk tiraxe:
Ayd gortsoxutyunn irakanatsnum en ayspes kochvats monoklonayin hakamarminnere kam mAbs-e, oronq i vitshaki en tarberelu qaxtskexayin bjijnere sovorakannerits:
«Monoklonayin» termine veraberum e bjijneri mek klonits mek hakamarmni krknorinaki stextsman gortsentatsin: Xosqe tsnoxakan mek yurahatuk bjji ev bjji masnatumits arajatsox hetnordneri masin e: Orosh monoklonayin hakamarminner ogtagortsvum en genayin inzheneriayi mej՝ tarber axbyurneri masere miavorelov buzhman hamar tsankali bnutagir unetsox mek nor hakamarmni mej:
Norzelandakan AgResearch petakan institutits Gyotts Layblei xekavarats hetazotakan xumbe hastatel e, or genayin modifikatsiayi entarkvats aytsere karox en artadrel qaxtskexe buzhox dexamijots՝ tsetuksimab: Nerkayums ayd dexamijotsov buzhume karox e arzhenal endhup minchev 13 hazar AMN dolar՝ amsakan:
Aytseri ognutyamb dexamijotsi zangvatsayin artadrutyan shnorhiv gitnakannere huys unen buzhel kolorektalayin qaxtskexe, toqeri qaxtskexe ev ayl hivandutyunner՝ aveli hasaneli gnerov: Layblen nshel e, or kendanineri ognutyamb tsetuksimab artadreln aveli matcheli klini, qani or nrants katnayin erkate karox e mets qanakutyamb spitakutsner artadrel:
Gitnakani xosqov՝ inchpes artadroxneri, aynpes el onkologiakan hivandutyun unetsoxneri hamar tsaxseri nvazetsume nor hetazotutyan himnakan sharzhich uzhn e dardzel:
Tsetuksimabn artadrman mej tankarzheq e och miayn ayn pattsharov, or laboratoriayum e stextsvum: Ayd nyuti spitakutsi qimiakan karutsvatsqn aynqan bard e, or dexagortsakan enkerutyunnern arandznahatuk monoklonayin hakamarminneri statstsman hamar kensabanakan mexanizmner en kirarum mkneri՝ hatuk modifikatsvats kultivatsvats bjijnerum: Layblen nshel e, or da erkaratev ev tsaxsatar gortsentats e: Katnasunneri bjijneri kultivatsman hamar verahskeli mijavayr e anhrazhesh, inche hangetsnum e artadrutyan ev tsavalman dzgdzgumneri:
Nor hetazotutyunum Layblen ev nra gortsenkernere naxatesum en transgenayin aytseri katits stanal qaxtskexi buzhman hamar anhrazhesht qanakutyamb spitakutsner, orpeszi nrants dardznen tsetuksimabi artadrutyan hamar npastavor hartak dardznen: Ayd nyute komertsion artadrutyunum haytni e Erbituks anvamb:
Kati mej mAb artadrelu hamar texekutyun pahpanox genere nerdrvel en aytsi bjijnerum, inchits gitnakannere stextsel kendani aytseri՝ ogtagortselov mievnuyn texnologian, inche haytni e dardzel Dolli aytsi klonavorman shnorhiv:
Layblen nshel e, or aytseri katits arandznatsvats mAb-e liovin gortsunya e, isk kendaninern aroxj en, chen tarbervum myusnerits:
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