Surtshi masin. taratsvats araspelner, haytni tvyalner u havasti vtangner

Endunvats e hamarel, or surtshi «zorutyan» masin arajinn imatsel e etovpiatsi hovive՝ tesnelov, or surtshi terevnere kerats aytsere gishere chen qnum: Na ayd masin patmel er vanakanin: Verjins pordzel er u hamozvel dranum: Da texi e unetsel 9-rd darum, sakayn surtshe hamashxarhayin tshanachum e statsel aveli ush:

Kofeine batsahaytel e germanatsi qimikos Ferdinan Rungen՝ 1819t., isk 1828t. fransiatsiner Peletyen ev Kavantun ayd nyute statsel en maqur vitshakum: Laborator paymannerum ayn karoxatsel e stnal Herman Emil Fishere:

Hakasutyunner

Batsahaytumnerits heto, sakayn shat hangamanqner derevs verjnakan patasxan chen statsel: Chapabazhni ev kirarman ardyunqneri veraberyal naxord dari tvyalnern arden hnatsel en:

Surtshi ev kofeini usumnasirutyunnere nerkayums nor tap en havaqel, inche himnakanum paymanavorvats e hamashxarhayin mets pahanjarkov: Artadroxnere erbemn sepakan hetazotutyunnern en katarum՝ ardyunqnere texadrelov och shat mejbervox amsagrerum: Dranq hatshax subyektiv bnuyt en krum: Surtshi azdetsutyan masin arajin ankax hetazotutyune hraparakvel e miayn 2012t.:

Ankax hetazotutyan tvyalnere

Kofeine nman e adenozin neyromediatri. drantsum amraktsman himqum adenini purinayin tsagumn e՝ DNT-i baxadrichnerits meke: Dra shnorhiv kofeine karox e kapvel nuyn retseptorneri het, oronts het ev՝ adenozine: Verjins kentronakan nyardayin hamakargi vra argelakox azdetsutyun e unenum, ashxatum e orpes verqeri kam stresneri yurahatuk pashtpan՝ kanxelov glxuxexi «gertaqatsume»:

Retseptorneri ayd tesaki het kapvum e naev kofeine, end orum՝ hstak mexanizme haytnabervel e miayn 2012t. verjin katarvats hetazotutyamb: Neyrofiziologiayi ev bzhshkutyan instituti germanatsi masnagetnere kirarel en pozitron-emisionayin tomografian (PET): Hetazotutyane kamavor masnaktsel e 15 txamard: Nranq 36 zham zerts en mnatsel surtshi kirarumits, inchits heto antskatsvel e PET՝ ftor-18-i (F-18-CPFPX) izotopov:

Aynuhetev masnakitsnerin nerarkel en kofein՝ erakits, astitshanabar metsatsnelov chapabazhine: Kofeinn amratsel e retseptornerin՝ durs mxelov F-18-CPFPX-e: Apa katarvel e PET: Ardyunqnere tsuyts en tvel, or 13 mg/l kofeini baxadrutyan depqum (espresoyi 4-5 bazhnin havasar) azat e mnum retseptorneri miayn 50%-e: Aydpisov՝ kofeine kentronakan nyardayin hamakargi vra anmijakan grgrich azdetsutyun chi unenum, miayn zhamanakavorapes kanxum e adenozini amratsume nra retseptorneri het ev argelakman efekti zargatsume:

Kofeine tmranyut och bolorn en hamarum, teev gitnakannere hangum en ayn ezrakatsutyan, or kofeinin varzhveln iskapes texi e unenum: Sakayn marde karox e aprel arants surtshi: Isk shat ogtagortsman depqum (orakan 300 mg kofeinits aveli) metsanum e adenozinayin retseptorneri tive:

Surtshits hrazharvelu depqum orosh zhamanakov aktivanum e adenozini argelakox hatkutyune, ore shutov zijum e. iravitshake verakangnvum e: Minchder kofeini charashahume karox e hangetsnel nuynisk mahvan: Masnagetneri hashvarknerov՝ mahvan elqi karox e hangetsnel 1,5 zhamum 1 kg espreso ogtagortsele:

Xelamit chaperov surtsh xmelu depqum sirte chi vtangvum: Hamenayn deps՝ minch ors hastatvats che batsasakan hetevanqe: Kayun hipertonia, sovorabar, chi tsagum:

Mardu hamar vtangavor e

Xmichqi kantserogenutyan hartse derevs bats e. ayn Qaxtskexi hetazotutyan mijazgayin gortsakalutyan koxmits nerarvats e kantserogenneri 3-rd xmbum. tesakanoren՝ mardu hamar vtangavor e, sakayn havasti ev verjnakan hetazotutyunner der chkan: Nuyn xmbum en naev bjjayin heraxosnere: Mievnuyn zhamanak՝ parzvel e, or surtshi siraharnere hatshax en tarapum shaganakagexdzi ev katnagexdzi agresiv qaxtskexov: Isk bazmativ hetazotakan xmber kofeine ditarkum en orpes hakaqaxtskexayin dexamijotsnere, orinak՝ depi glxuxexe hastsnelu mijots:

Oroshaki zgushavorutyun, amen depqum, hastatvel e. orinak՝ hxinerin xorhurd chi trvum orakan 200 mg kofeini chapabazhine gerazantsel, qani or batsasabar e azdum ptxi vra, masnavorapes, metsatsnum e «napastaki shrtunqov», srti aratov erexayi tsnundi vtange: