Gitnakannere parzel en, te inchu en avelord qash unetsoxnere tsanr tanum Covid-19-e

Bardzr tariqe, tsxele, avelord qashe ev xronik hivandutyunneri arkayutyune (masnavorapes՝ sirt-anotayin hamakargi, shaqarayin diabet) nor tesaki koronavirusov varakvats patsientneri hamar mahatsutyan ev bardatsumneri vtangi himnakan hangamanqnern en: Aveli vax AMN-i gitnakannere hamarel en, or Covid-19-i tsanr entatsqov hospitalatsvatsneri sharqum aveli hatshax en handipum tsharpakalutyamb tarapoxnere:

Nerkayums Kanadayits ev Arabakan Miatsyal Emirutyunnerits kensabannere oroshel en parzel, te inchov e paymanavorvats Covid-19-ov varakvatsneri hamar hivandutyan tsanr depqeri haxtaharume, ev hastatel en, or gereri organizme retseptorneri bardzr qanak e mshakum, oronq anhrazhesht en SARS-CoV-2-in՝ aroxj bjijneri mej soxoskelu hamar: Hetazotutyune derevs graqnnutyun chi antsel:

Ashxatutyan hexinaknere nshum en, or aveli vax tsuyts e trvel, or bjij-tiroj mej mutq gortselu hamar SARS-CoV-2-n ogtagortsum e 2-rd angiotenzinpoxakerpox fermentnerin (membranayin spitakuts ACE2): Nranq pordzel en nkaragrel, te inchpes e SARS-CoV-2-e xaxtum tiroj mot lipidneri nyutapoxanakutyan uxinere ev inchpes e apakargavorvats lipogenese (tsharperi kutakman gortsentats) azdum ACE2-i kargavorman vra, hatkapes giranalu depqum:

Hexinakneri xosqov՝ hanramatcheli transkriptomayin tvyalneri krknaki verlutsutyan ognutyamb arajin angam batsahaytvel e, or SARS-CoV-2-ov varakvats toqeri epitelayin bjijnere tsutsaberum en ayn generi bardzr kargavorum, oronq kapvats en lipidneri nyutapoxanakutyan het, neraryal SOC3 gene, ore masnaktsum e borboqman kargavormane ev leptini azdanshanneri poxantsman zspmane:

Gitnakannere pordzarkum en arel 16 laborator mkneri vra, oronts bazhanel en 2 havasar xmbi: Haytnabervel e, or arajin xmbi՝ tsharpakalmamb tarapox krtsoxneri organizme avelord qash chunetsox mkneri xmbi het hamemat aveli shat ACE2 fermentner e artadrel, oronts het poxgortsaktsum en koronavirusi S spitakutsnere: End orum՝ da aveli shat nkatvel e toqeri hyusvatsqnerum: Aydpisov, virusn ir tirapetutyan tak organizm nertapantselu aveli shat uxiner e unetsel:

Hetazotutyan hexinaknere entadrel en, or nman gortsentatse karox e ditarkvel naev diabetov hivandneri organizmum ev aryan mej xolesterini bardzr qanak unetsoxneri mot: Kensabannere naxatesum en da parzel hetaga hetazotutyunnerum:

Aveli vax Londoni kayserakan qolejits profesor Piter Openshoun nshel e, or, amenayn havanakanutyamb, nerqin organneri shurje tsharpi avelatsumn uzhexatsnum e Covid-19-i arajatsrats «tsitokinayin potorike»: Hipertsitokinemian chverahskvox borboqayin reaktsia e, orn arajatsnum e organizmi sepakan hyusvatsqneri vnasum:

Virusi dem payqarelu hamar organizme sksum e arandznatsnel tsitokinneri molekulnere, oronq apahovum en bjijneri՝ interferonneri, interleykinneri, hemokini ev aylni mijev poxazdetsutyunnere: Tsitokini azdetsutyamb bjije sksum e artadrel ayl tsitokinner. sksvum e ayspes kochvats tsitokinayin potorik, ore karox e hangetsnel bazmaorganayin anbavararutyan, hiperferitinemiayi, inchpes naev mahvan:

Batsi ayd՝ naxord hetazotutyunnere tsuyts en tvel, or giratsats mardik skzbunqoren hatshax en tarapum bardatsumnerits kam mahanum varakayin hivandutyunnerits, inchpisin gripn e: Avelord qashe naev dzhvaratsnum e ttvatsni nershnchume, isk dra anbavararutyan pattsharov hyusvatsqneri ev organneri mot ditvum e disfunktsia: Bolor ayd hangamanqnern endhanur armamb karox en batsatrel, te inchu en avelord qash unetsox patsientnere Covid-19-n aveli tsanr tanum: