Hetazotoxnere hastatel en, or koronavirusi pandemian bnakan pattsharner uni

Amboxj ashxarhum pandemiai pattshar dardzats SARS-CoV-2 virusi tsagman veraberyal bazmativ varkatsner en araj qashvel: Masnavorapes, tarberak ka, or ayn arhestatsin e ev stextsvel e laboratoriayum: Sakayn usumnasirutyune tsuyts e tvel, or ays viruse bnakan evolyutsiayi ardyunq e:

Gitnakanneri mijazgayin xumbe SARS-CoV-2-i ev nra «harazat» virusneri genomi hajordakanutyan hamematakan hetazotutyun e antskatsrel: Hetazotoxnere och mi nshan chen haytnaberel ayn bani, or vtangavor patogene karox e sintetik tsagum unenal: Kaliforniayi Skripsi gitahetazotakan instituti ashxatakits, usumnasirutyan hexinaknerits Qristian Andersene nshel e, or kareli e pndel՝ SARS-CoV-2-n arajatsel e bnakan gortsentatsneri ardyunqum:

Irents ashxatanqi entatsqum gitnakannern usumnasirel en virusayin taxanti pshanman spitakutsneri generum RNT-i masere: Da virusi himnakan makeresayin proteinnern en, oronq anhrazhesht en bjji het kapvelu ev nra mej soxoskelu hamar: Hetazotoxnerin arajin hertin hetaqrqrel e nukleinattvi hajordakanutyune, oronq kodavorum en pshanman spitakutsneri (RBD) retseptor-amraktsox domene, inchpes naev hajordakanutyune, ore hamapatasxanum e tshexqman kayqerin. «pahatsoyi molekulyar danakner», oronts ognutyamb viruse ochnchatsnum e bjji taxante:

Parzvel e, or virusayin spitakutsneri RBD domene evulyutsiatsrel e aynpes, or aravelaguyns ardyunavet kerpov poxazdvi ACE2 retseptorneri het` tiroj bjijneri makeresin: Bnakan evolyutsiayi apatsuytse statsvel e SARS-CoV-2-i endhanur molekulyar karutsvatsqits: Ete entadryal «kensaahabekichnere» pordzein hnarel mardaspan virus, nranq da kanein arden haytni patogeni himan vra՝ apatsutsvats varakunakutyamb:

Sakayn gitnakannere hastatum en, or SARS-CoV-2-i «molekulyar himqe» nshanakalioren tarbervum e mardu nmanatip virusneri mets masits: Ayn himnakanum hishetsnum e ayn harazat virusnerin, oronq haytnabervel en chxjikneri ev soxunneri mot: Andersene nshel e, or virusi nman arandznahatkutyunnere batsarum en laborator manipulyatsianere, inchpes SARS-CoV-2-i hnaravor tsagum:

Virusi arajatsman aravel havanakan tarberak e hamarvum erku hnaravor varkatsnerits meke: Arajini hamadzayn` virusn astitshanabar popoxvel e naxord tiroj (amenayn havanakanutyamb՝ chxjiki) organizmum՝ dzerq berelov bardzr patogenutyun, inchits heto poxantsvel e mardun: Aydpes en arajatsel naev naxord xoshor brnkumnere, orinak՝ SARS-CoV-e (atipik toqaborb) mardik statsel en vivernerits, isk MERS-CoV-e՝ uxterits:

Myus dipasharov` viruse mardkayin populyatsiayum e haytnel och patogen vitshakum ev nranum arden evolyutsiayi entarkvel: Ayd hipotezi hastatume gitnakannere haytnaberel en tepamortneri mot. orosh koronavirusneri RBD-domennere, oronq taratsvum en ayd kendanineri mot, nman en SARS-CoV-2-i spitakutsneri nuynatip maserin: Hnaravor e՝ tepamortnerits viruse mardkants e poxantsvel mijankyal tererits, isk nra veradzevman kayqere pshanman spitakutsnere mutatsrel en aveli ush:

Ete SARS-CoV-2-e mardu organizmum haytnvel e arden ir nerkayis patogen karutsvatsqov, apa da apaga brnkumneri havanakanutyune metsatsnum e, qani or virusi՝ hivandutyunn arajatsnox shtamme der karox e shrjaptuyt gortsel kendanakan ambarnerum: Havanakanutyune, or och patogenayin koronaviruse mardkayin populyatsia e mutq gortsel ev dzerq berel SARS-CoV-2-in bnorosh hatkanishner, eakanoren poqr e: Sakayn derevs hetazotoxnere patrast chen haytnelu, te erku dipasharerits orn e texi unetsel: